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Tamoxifen: Questions and Answers
Information courtesy National Cancer Institute Fact Sheet (NCI) Source: www.cancer.gov
Reviewed: 03/17/2008
Tamoxifen: Questions and Answers
Key Points
Tamoxifen (Nolvadex®) is a drug that interferes with the activity of estrogen, a female hormone. Tamoxifen has been used for more than 30 years to treat breast cancer in women and men (see Question 1).
Tamoxifen has been used for almost 10 years to reduce the risk of breast cancer in women who are at increased risk of developing breast cancer (see Question 1).
The known, seri......[more]
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Skin Cancer Prevention: Dana-Farber experts offer tips to protect yourself in the sun
Prevention and early detection are critical to reducing the dangers of skin cancer and melanoma....[more]
Angiogenesis Inhibitors Therapy: Questions and Answers
Angiogenesis plays an important role in the growth and spread of cancer. New blood vessels “feed” the cancer cells with oxygen and nutrients, allowing these cells to grow, invade nearby tissue, spread to other parts of the body, and form new colonies...[more]
Researchers Find that a Small Molecule Can Activate an Important Cancer Suppressor Gene
By activating a cancer suppressor gene, a small molecule called nutlin-3a can block cancer cell division, according to researchers at the National Cancer Institute (NCI), part of the National Institutes of Health. This activation of the p53 g...[more]
Childhood leukemia survivors struggle with long-term side effects
Acute lymphoblastic leukemia (ALL) is the most common childhood leukemia and childhood cancer overall, accounting for about one-fourth of all pediatric cancers. Each year about 3,000 new cases are diagnosed in the U.S., though recently the cure rate ...[more]
Colon cancer screening key to prevention, increased survival
Researchers, including those at the University of Michigan Comprehensive Cancer Center, are working to make colorectal screening a little easier, through a combination of more choices and ...[more]
Breast Cancer: Cardiac Effects Associated with Chemotherapy Treatment Lower With Dose-Dense Delivery
NEW YORK - A new pilot study by investigators at Memorial Sloan-Kettering Cancer Center (MSKCC) found that breast cancer patients can be treated safely with a "dose-dense" regimen of standard chemotherapy agents and the antibody trastuzumab (Hercepti...[more]
Leukemia News: Molecular science could further improve leukemia survival, say St. Jude researchers
The dramatic increase that has occurred in the cure rate for children with acute lymphoblastic leukemia (ALL) will be difficult to replicate in older patients without considerable additional research, according to an article by St. Jude Children’s Re...[more]
Prostate Cancer Research: Hormone independent prostate cancer more likely to spread
Prostate cancers that are resistant to androgen deprivation therapy are more invasive and more likely to spread to other organs than androgen dependent prostate cancers, UCLA cancer researchers have found....[more]
Jobs with increased activity may decrease risk of prostate cancer
Men with jobs that require them to be physically active may be getting benefits beyond salary and health insurance - they may be at a decreased risk of developing prostate cancer, according to a study at UCLA’s Jonsson Cancer Center....[more]
Inflammatory Breast Cancer: Questions and Answers
Inflammatory breast cancer is a rare but very aggressive type of breast cancer in which the cancer cells block the lymph vessels in the skin of the breast. This type of breast cancer is called “inflammatory” because the breast often looks swollen and...[more]
Prostate Cancer Risk: Research finds genetic links
Researchers report that a set of genetic variations in at least four regions of DNA strongly predicts prostate cancer risk and that these variations may be responsible for a large number of prostate cancer cases in white men in the United States. Th...[more]
Oral Contraceptives and Cancer Risk
Oral contraceptives (OCs) first became available to American women in the early 1960s. The convenience, effectiveness, and reversibility of action of birth control pills (popularly known as “the pill”) have made them the most popular form of birth co...[more]
Cells lining milk ducts hold key to spread of common form of breast cancer, study finds
The discovery, reported in the May 6 issue of Cancer Cell, may lead to screening tests to determine whether the disease -- known as ductal carcinoma in situ, or DCIS -- is likely to spread beyond the ducts, based on genetic abnormalities in cells in ...[more]
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